Found in the Death Valley region and the adjoining Panamint Valley, bristly calico is another of the tiny desert annuals that can be easily missed by the casual observer. This species is the sole member of its genus, which contains two sub-species. In the other sub-species, L. setosissima subsp. setosissima has fainter speckling on its petals, but is otherwise indistinct. These plants can be anywhere from 4-20 cm tall, with the flowers being 1.5-2cm in diameter. They are typically found on rocky slopes and washes of the eastern California deserts and up into Oregon and Idaho, and east into Nevada and Arizona.
Like most desert annuals and smaller plants, this species has very little in the way of documentation for this plant.